This 48 kilometre route, with an altitude difference of 750 metres, can be considered of medium difficulty due to the continuous climb and, in particular, the climb up to Panicale, which has to be done twice up two different hills.

From Panicale you descend towards Lake Trasimeno along a road with very little traffic, allowing you to admire fascinating views of the lake contrasting with the green of the cultivated fields and surrounding hills.

After a few kilometres around the lake, the road heads off towards the south, passing through the small villages of Mugnano, famous for its painted walls, and Fontignano, where the grave of the painter Perugino can be found, before returning to Panicale up a hill that winds its way through the olive trees, where a series of hair-pin turns allows you to catch your breath. Here one can decide whether to stop or to continue the ride to Paciano, one of the 'most beautiful villages of Italy': the panoramic road and the beauty of the old village centre will make all the effort worthwhile